Patric Hornqvist scored a pair of goals in the Penguins' 4-2 win over the Sabres in Buffalo.
Sidney Crosby and Marcus Pettersson scored the other goals for Pittsburgh, which has won two in a row after a six-game skid.
Nick Bjugstad returned to the Penguins after missing 46 games with a core muscle injury and had an assist in 11-minutes ice time.
The Penguins return home tomorrow night to face the Capitals and Sunday will host the Hurricanes.