The Indians extended their lead on the Twins in the AL Central with an 8-1 win to open a three-game series at Target Field. Cleveland is now six games up on Minnesota.
The Indians were powered by five home runs, including two from Carlos Santana. Austin Jackson, Jason Kipnis and Edwin Encarnacion also left the yard.
Danny Salazar improved to 5-and-5, cruising through seven innings of one-run ball and striking out 10.